Abstract

Renal failure occurs when the kidneys becomeunable to filter waste products and excess fluids from the bloodin an effective way. It can be caused by many medical problemssuch as diabetes, and hypertension. Exposure to heavy elementsis another causative factor. Fifteen patients with chronic renaldisease on dialysis were involved in the study (12 males and 3females) aged between 26 and 74. Complete medical history wastaken from all. The control group involved eight healthy adultsaged between 33 and 47. Serum and urinary lead and cadmiumbefore and after dialysis (for patients) were taken and once forcontrol, samples were analyzed by using an atomic absorptionspectrophotometer. Results for Lead show that by comparingpre-dialysis to post-dialysis state, there was a significantreduction in mean serum lead (Pb) from 0.04±0.04 to 0.01±0.01,respectively (<em>p </em>= 0.011), which becomes nearly similar to thecontrol group. For urinary samples, there was a significantreduction in mean urinary lead (Pb) from 0.88±0.95 to0.22±0.37, respectively (<em>p</em> = 0.010), which also becomes nearlysimilar to the control group. For Cadmium by comparingpre-dialysis to post-dialysis state, there was no significantreduction in mean serum cadmium (Cd) from 0.03±0.05 to0.00±0.00, respectively (<em>p</em> = 0.086), which becomes nearlysimilar to the control group. And for urinary samples, there wasa significant reduction in mean urinary cadmium (Cd) from0.02±0.03 to 0.01±0.01, respectively (<em>p</em> = 0.010).