General Information
    • ISSN: 2010-0264
    • Frequency: Bimonthly (2010-2014); Monthly (Since 2015)
    • DOI: 10.18178/IJESD
    • Editor-in-Chief: Prof. Richard Haynes
    • Executive Editor: Ms. Nancy Y. Liu
    • Abstracting/ Indexing: Chemical Abstracts Services (CAS), CABI, Ulrich Periodicals Directory, Electronic Journals Library, Crossref, ProQuest.
    • E-mail:
  • Dec 04, 2017 News! The Annual Meeting of the IJESD Editorial Board (ACESD 2017) was held successfully. I would like to express my sincerely appreciation for your support to our conference.   [Click]
  • Apr 12, 2018 News! Vol. 9, No. 5 has been indexed by Crossref. 
The University of Queensland, Australia
It is my honor to be the editor-in-chief of IJESD. The journal publishes good papers in the field of environmental science and development.
IJESD 2015 Vol.6(4): 316-320 ISSN: 2010-0264
DOI: 10.7763/IJESD.2015.V6.610

Cellular and Molecular Damage by Ganaxolide on Phanerochaete Chrysosporium

Hongxia Xiong, Changbing Liu, Aijing Li, Yu Lin, and Wei Huang
Abstract—Galaxolide (1, 3, 4, 6, 7, 8-hexahydro-4, 6, 6, 7, 8, 8-hexamethyl-cyclopenta-γ-2-benzopyran, HHCB) is recognized as a novel contaminant in water and has potential adverse impacts on aquatic organisms. The toxic effect of HHCB on Phanerochaete chrysosporium was investigated by exposure of the fungus in nitrogen-limited culture medium to various concentrations of HHCB. The cultivation results showed that both the size and the quantity of the mycelial pellets of P. chrysosporium could be reduced when the concentration of HHCB was higher than 300 mg/L. DNA damage of P. chrysosporium by HHCB was also detected. Comparing with that in the control, the percent polymorphism under different concentrations of HHCB increased, from 21.4% to 42.9%. In addition, the result of UPGMA (un-weighted pair group method of arithmetic means) dendrogram showed that the Simple Matching Coefficient (SM) was decreased with an increase in the concentrations of HHCB. Thus, as an environmental pollutant, HHCB has the toxic effect on P. chrysosporium at both cellular and molecular level.

Index Terms—AFLP, Phanerochaete chrysosporium, HHCB, DNA damaging effects.

Hongxia Xiong, Changbing Liu, Aijing Li, Yu Lin, and Wei Huang are with the Tianjin Research Institute for Water Transport Engineering, Key Laboratory of Environmental Protection in Water transport Engineering, Ministry of Transport, Tianjin 3, China (e-mail:, {632528078, 86055991,681137438},


Cite:Hongxia Xiong, Changbing Liu, Aijing Li, Yu Lin, and Wei Huang, "Cellular and Molecular Damage by Ganaxolide on Phanerochaete Chrysosporium," International Journal of Environmental Science and Development vol. 6, no. 4, pp. 316-320, 2015.

Copyright © 2008-2018. International Journal of Environmental Science and Development. All rights reserved.